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The USB scales that we support (Stamps.com, DYMO, and Mettler-Toledo) typically do allow data transfer via USB and work with our scale integration called ConnectEasy:
For example, this scale:
Under specifications says "Connect via USB cable to PC or Mac®* to use the scale with popular online mailing and shipping software – including DYMO Stamps®*** software."
Once you have a scale, you can test it out and get the weight reading in ShippingEasy. Steps for doing that can be found in the article linked below: