Thank you for posting to our forums!
I see you are trying to generate FedEx labels and unfortunately, FedEx is having issues today. There is a red alert at the top of ShippingEasy that says "FedEx is experiencing problems in their data center. Rate quotes and label purchases for FedEx shipments may be delayed or unavailable."
We've reached out to FedEx and found that they are aware of the problem but they do not currently have an ETA for it to be resolved. This issue is affecting all customers who use the FedEx API (not just ShippingEasy).
I would recommend trying the labels again later or using a different carrier for those particular shipments. Hopefully FedEx will have their API up and running again soon!